BDBM12028 4-Arylazo-3,5-diamino-1H-pyrazole 31b::4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]phenol::CAN508

SMILES Nc1n[nH]c(N)c1N=Nc1ccc(O)cc1

InChI Key InChIKey=AYZRKFOEZQBUEA-UHFFFAOYSA-N

Data  2 KI  11 IC50

PDB links: 4 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12028   

TargetCyclin-dependent kinase 9(Homo sapiens (Human))
Institute of Experimental Botany Ascr and Palacky University

LigandBDBM12028(4-Arylazo-3,5-diamino-1H-pyrazole 31b | 4-[(E)-2-(...)Copy SMILESCopy InChI

Affinity DataIC50:  350nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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